Aging Matters
Senolytic drugs have been the most promising near-term anti-aging therapy since the ground-breaking paper by van Deursen of Mayo Clinic published in 2011. The body accumulates senescent cells as we age, damaged cells that send out signal molecules that in turn modify our biochemistry in a toxic, pro-inflammatory direction. Though the number of such cells … Read more
This is the most important column I’ve ever written. The message is quite complex–dozens of new health parameters to test for and to optimize, all of them interacting in ways that will require new training for MDs. The message is also as simple as it can be: There is a cure for Alzheimer’s disease. You … Read more
I’ve been in the field of aging research from the late 1990s, just the time when Aubrey de Grey was getting his start. Before others, Aubrey had the vision to realize that cancer, heart disease, and Alzheimer’s would never be conquered without addressing their biggest risk factor: aging. From the beginning, I admired Aubrey’s successes … Read more