Putting the brakes on cell suicide

An eminent Russian biochemist has been working fifteen years to get the cell’s most active anti-oxidant into the mitochondria, which is the locus of its action. Called “SkQ” for short, his designer drug administered in food, has been shown to make mice live longer; and topically it can induce regression of eye diseases in rodents, … Read more

How Can We Stop Killing Ourselves?

Last week, I wrote aspects of aging that appear to be active self-destruction.  I mentioned four such processes that might make promising targets for anti-aging therapies: inflammation, immune derangement, cell suicide (or apoptosis) and telomere shortening. I promised more detail to follow We used to think the body wears out with accumulated damage. In order to … Read more

Is Aging an Active Process of Self-destruction?

Most people think of aging as passive – something that happens to your body. Random mutations occur faster than the body can fix them. Cholesterol deposits build up in the arteries. Above all, oxidation damages the body’s delicate chemistry, and this affects the ability to fix other damage. But a new view is emerging, in … Read more