This new video introduces my work in the context of a hundred years of evolutionary theory and the breakthrough rejuvenation science in the present.
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Aging Matters
This new video introduces my work in the context of a hundred years of evolutionary theory and the breakthrough rejuvenation science in the present.
Subscribe to get the latest posts sent to your email.
This is wonderful, Josh. Thank you (and thank you too for pronouncing ‘apoptosis’ correctly 🙂 )
Fisetin is known to have low bioavailability. It’s suggested to take it with some fat, such as fish oil to improve bioavailability. However, to my knowledge this would break your fasting. Josh, can you please share how you take Fisetin during your fasting routine?
I know you were asking Josh this question, but I thought I’d put in my two bits’ worth.
Valter Longo’s “fasting-mimicking” diet provides many of the benefits of true fasting without the harsh exit from and re-entry to normal feeding. As it is relatively permissive of fats/oils within the caloric limits of the dietary framework, it is ready-made for optimizing fisetin absorption.
I don’t mean to suggest that you switch from true fasting to the fasting-mimicking diet, but this does suggest that taking a small amount of fat/oil with some fisetin during a true fast would have relatively little impact on the beneficial effects of short-term starvation.
Thanks for alerting me. I wasn’t aware of this issue. I chose fisetin over quercetin because I thought it was more easily absorbed, relatively.