How we know that aging is a biological function, and why it matters

This new video introduces my work in the context of a hundred years of evolutionary theory and the breakthrough rejuvenation science in the present.


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4 thoughts on “How we know that aging is a biological function, and why it matters”

  1. Fisetin is known to have low bioavailability. It’s suggested to take it with some fat, such as fish oil to improve bioavailability. However, to my knowledge this would break your fasting. Josh, can you please share how you take Fisetin during your fasting routine?

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    • I know you were asking Josh this question, but I thought I’d put in my two bits’ worth.

      Valter Longo’s “fasting-mimicking” diet provides many of the benefits of true fasting without the harsh exit from and re-entry to normal feeding. As it is relatively permissive of fats/oils within the caloric limits of the dietary framework, it is ready-made for optimizing fisetin absorption.

      I don’t mean to suggest that you switch from true fasting to the fasting-mimicking diet, but this does suggest that taking a small amount of fat/oil with some fisetin during a true fast would have relatively little impact on the beneficial effects of short-term starvation.

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