Growth & Aging; Creatine & Health

Prologue Promoting growth is dangerous, especially if it is done in an un-natural way. “Hormones and growth signals are tightly constrained, and highly optimized by evolution.  Too little and the body atrophies over time, failing to renew muscle and nerve tissues.  But too much and the body risks overstimulating some rogue cell, which may turn … Read more

Promise of Novel Alzheimer’s Treatments

Last year, I blogged on a CDC report that Alzheimer’s Disease is more prevalent than previous epidemiology had acknowledged.  Last month at the Rejuv Biotech conference, I heard Chas Bountra tell us that Alzheimer’s Disease is currently #3 among diseases of old age Demographics are increasing the prevalence of AD at an inexorable rate Far … Read more

Untested Treatments for Longevity, and How to Test Them

Tests with human subjects require decades, and are impossible to control, so the  gold standard for testing claims for treatments that delay aging is the controlled trial with rodents, usually mice.  Each treatment is applied to about 50 mice for their 2-3 year life span, and an equal number of controls is housed in identical … Read more

HGH and IGF–Promise and Danger

In the 1980s, Growth Hormone was explored by athletes to build muscles and by aging men to…build muscles.  GH made them feel younger, revived energy and sex drive and even cognitive performance.  Then the other shoe dropped:  Animals without the GH receptor lived longer, while animals with extra copies of the GH gene die early. … Read more