Epigenetics and the Direction of Anti-Aging Science

Dear Readers – It’s been a deeply gratifying year for me.  Twenty years ago, I first started writing that aging is something the body does to itself, a body function, rather than deterioration or loss of function.  Journals would not even send my submission out for peer review.  Journal of Theoretical Biology sent me the … Read more

From Santa Diego, a Jolla Xmas Gift

From the Salk Institute in La Jolla, CA came an announcement last week that the four factors previously identified to turn ordinary cells into stem cells (in cell cultures) was successfully used as a rejuvenation procedure in live mice.  The results provide important new evidence for the hypothesis that aging is under epigenetic control, and … Read more

Telomeres—too much of a good thing?

One of the major themes in aging science of the last 15 years has been that there is natural variation in telomere length, and individuals with longer telomeres have lower disease risk and longer life expectancy than those with shorter telomeres.  A paper last week in Nature Structural and Molecular Biology found that stem cell … Read more