Lifespan of Harold Katcher’s Rats

Preliminary results from lifespan studies with E5 Harold Katcher has developed a protocol for lab rats using intravenous injection with a blood plasma fraction he calls “E5”. Three years ago, he announced that treated rats evinced many features of rejuvenation, including improvements in grip strength, endurance, and learning capacity. Two years ago, he announced that … Read more

Is there a master timekeeper, upstream of the methylation clock?

I have promoted the idea that aging is programmed and that the program is epigenetic. Hence epigenetic age is fundamental. But what is it that imprints epigenetic age on the chromosomes and keeps it updated? Is the “methylation clock” responding to a higher authority, a separate clock which coordinates epigenetic age throughout the body? Do … Read more