Month: February 2018

Methylation of DNA is the best-known mode of epigenetic regulation (turning genes on and off).  Methylation patterns are stable unless they are actively changed, and can persist over decades, even across generations.   Four years ago, biostatistician Steve Horvath of UCLA identified a set of 353 methylation sites that are best-correlated with human (chronological) age.  These … Read more

The Most Promising Way Forward for Anti-Aging Science Today We now have many effective interventions (mostly of small effect) for longevity and preventive care.  Most readers of this blog take more than one supplement each day; some of us (I confess) take very many.  We make an unthinking assumption that “more is better”, or rather … Read more