Aging Matters
A study out of Nanjing University last month brings exosome rejuvenation to the mainstream of researchers with broad new evidence and some speculations on mechanisms. The prominent publication in Nature Aging corroborates and greatly expands results from Harold Katcher’s Mumbai lab. Massive infusions of exosomes from young mice into old improve cognition, endurance, fertility, energy metabolism, heart … Read more
Of the many species that outlive their fertility, lab worms (C elegans) take the cake. They stop laying eggs after two days, but they can go on to live for two more weeks. Did they miss school the day that the teacher was lecturing on Darwinian fitness? Or perhaps do the elders of their community … Read more
Spermidine is found naturally in many foods. Blood levels decline with age. Supplementation extends lifespan and healthspan in various species, and lowers mortality in human trials. I have been unable to find toxicity data or any downside to spermidine supplementation, except that the effective dosage may be impractical. “Consistently across species, extra supply of spermidine … Read more