Prolonging Life with Fecal Transplants

A game-changing result this week from the laboratory of Dario Valenzano (Max Planck Inst).  A single treatment of antibiotics in middle-aged fish followed by transplant of gut bacteria from young fish resulted in extension of mean lifespan by 41%, max lifespan by 30%.  Treated fish remained active at ages where untreated fish were slowing down. … Read more

Is fasting senolytic?

I am finishing a four-day fast today.  In the hope of synergizing senolytic modalities, I took 2.5 g of quercetin last night and another 2.5 g this morning.  I don’t take quercetin regularly, because studies in mice show that daily administration doesn’t lengthen lifespan, and may shorten it.  But for the present, quercetin is the … Read more