The Carrot and the Stick

Sex is so important to the health of a breeding community that natural selection has arranged to encourage everyone to participate.  There’s a conflict here, because the selfish gene does not want to share.  The strongest and most fertile individuals–anyone who has an advantage in the present environment–is tempted not to dilute her genes by … Read more

CRISPR in your Future

CRISPR is a two-year old technology developed at Berkeley, Harvard Stem Cell Inst and elsewhere, that is making genetic engineering faster, simpler, and more accurate in the lab.  Last year, they figured out how to insert and delete genes.  This year there are methods for repressing and perhaps promoting genes (epigenetically, without modifying the genome) … Read more

Sleep and Longevity

Good quality sleep, 6-8 hours per night but not more, is statistically associated with longevity.  Is there a causal connection?  Experiments with rats and data from people doing shift work suggests that yes, there is. But how to get good sleep, and even what good sleep means varies widely from one person to the next. … Read more

Transfusing Youth: the epigenetic aging clock hypothesis is about to be tested

Just this past Spring, Tony Wyss-Coray of Stanford demonstrated that infusions of blood plasma from young mice can make old mice grow new brain tissue.  Others have demonstrated benefits for muscle and liver health. The old mice are healthier, smarter, better healers for the infusion of hormones and dissolved factors (not blood cells) from the … Read more